What Is Modalert?

Modalert is a generic version of modafinil made by the pharmaceutical giant, Sun Pharmaceuticals.

It comes in 100 mg, 200 mg, and 400 mg sizes, though most vendors sell the 200 mg version only. Each capsule comes with a convenient crease down the middle, so users can easily separate their 200 mg tablets into two equal 100 mg doses if they want a smaller dose.

Modalert is prescribed for treating ADD/ADHD and narcolepsy by doctors. Outside of its prescribed uses, Modalert is popular as a cognitive enhancement supplement. It’s also used by the US military to help their special forces stay awake during long missions.

Students often take Modalert to improve their focus during study sessions. Business executives use it to power through exhausting projects, and gamers use it during competitions to increase their vigilance and reaction times.

Where To Buy Modalert

There are many vendors selling modafinil online — some are excellent, others not.

Some vendors like Afinil Express offer free shipping, and guaranteed deliveries to the United States, UK, and Australia. They also offer a 10% discount to returning customers, and an additional 20% discount for orders purchased with Bitcoin.

Most vendors will sell generic versions of modafinil such as

• Modalert
• Modvigil
• Waklert
• Artvigil

Should you decide to order from Afinil Express, be sure to use our discount code MODAFINILOTC to save 10% on your entire order. 

Is Modalert Legal?

All forms of modafinil are considered prescription-only medications in the United States, Australia, Canada, and most of Europe.

Modalert can be purchased online through vendors operating in places where the sale of modafinil is open to the public—most commonly, India.

How Much Does Modalert Cost?

The main difference between the brand name modafinil (Provigil®) and Sun Pharmaceuticals generic version (Modalert) is the price.

Chemically, Modalert is the same as brand name modafinil, Provigil®.

In the past, the only option available to people prescribed modafinil was Cephalon Inc’s expensive Provigil®, often costing around $51 per tablet.

In recent years, thanks to the convenience and accessibility of the internet, Modalert (Sun Pharmaceuticals) can be bought with or without a prescription at the low cost of $0.98-$2.80 USD per tablet.

Ordering Modalert Online

When buying Modalert online, it’s important to find a vendor that will ship to your country. In some parts of the world, such as Japan, Russia, or China, modafinil is strictly prohibited, and therefore most vendors won’t ship to these regions.

In places like the United States, The UK, Finland, Australia, or Sweden, most online vendors will guarantee the arrival of their customers’ order.

Occasionally, border security officers will confiscate a package, however, since the drug isn’t illegal to own, no further action will result.

High-quality modafinil vendors will offer refunds on orders confiscated at the border, or they will simply re-ship the same order a second time.

Though inconvenient, most people rarely experience any issues receiving their orders.

Some countries, such as Canada, are notorious for their attention to incoming mail, and often confiscate orders of Modalert before they reach their final destination. For this reason, many modafinil vendors won’t ship to Canada.

How Modalert Works

Medications often work by binding to specific receptors in the body. The body uses different types of receptors to tell the cells what to do.

Modalert works on a special set of receptors called “dopamine transport receptors”

These receptors tell the neurons how much dopamine they should reabsorb (thus reducing the concentrations of dopamine). When Modalert enters the body, it blocks these receptors, preventing the reabsorption of dopamine. As less dopamine is reabsorbed into the cell, it begins to build up outside of the cell.

Cocaine uses the same mechanism to exert its effects, though to a much stronger degree. If we could imagine a dial in the brain controlling wakefulness, modafinil is about a 6, while cocaine is so powerful whole dial breaks off.

There are also several other mechanisms Modalert uses to boost cognitive function and wakefulness that make it very different than cocaine.

Modalert also increases histamine, orexin, and norepinephrine in the brain. These chemicals are used to regulate the arousal portion of the sleep-wake cycle. [1-3].

The conditions modafinil is prescribed for involve deficiencies in one or more of these neurotransmitters. ADD/ADHD sufferers often have below-average dopamine levels, and narcolepsy sufferers have low orexin.

 

How Much Does Modalert Cost?

Compared to other versions of modafinil, Modalert is slightly more expensive on average.

Places like Afinil Express offer different quantities of Modalert. Higher quantities come with more cost savings per pill.

The smallest order, which comes with 50 tablets, is priced at $2.80 per tablet. The highest quantity, 500 tablets, costs only $0.98 per tablet.

Afinilexpress.com offers free shipping, and a 20% discount if payment is made with Bitcoin. Additionally, a 10% discount is given to all returning customers.

Using our discount code: MODAFINILOTC at checkout saves you an additional 10% off your order.

These discounts bring the cost of Modalert down as low as $0.68 USD per tablet of Modalert.

How Much Modalert Should I Take?

The recommended dose for Modalert is 200 mg, though some prefer to cut the tablets in half and take 100 mg doses (better for sensitive individuals or long-term use). Other people choose to double down and take 400 mg doses (suited for larger people, or single doses every now and then).

Although Modalert is considered safe, it’s recommended that users follow the directions on the packaging to avoid overdose.

Modalert vs Modvigil vs Provigil®

There are other versions of modafinil as well, including the HAB Pharmaceuticals generic version (Modvigil), as well as the brand name version (Provigil) by Cephalon Inc.

From a chemical standpoint, there are few differences between these drugs. They often come in the same 200 mg dose and use similar fillers and binders (used to help the tablets stay formed or avoid clogging the machines used to make it).

The major difference between these products is the price.

Modvigil is the cheapest option, coming in at around $0.80–$2.10 per capsule on AfinilExpress.com (depending on how much you order at a time). Modalert is the next in line, with a small increase in price to $0.98–$2.80 per tablet.

Provigil®, on the other hand, is very expensive. It costs an average of $51 for the same 200 mg tablet.

Why is Provigil® so expensive?

The steep price tag comes with being a brand name product.

This practice is as common in the drug industry as it is in other industries like clothing or cars. Some brands offer their goods at significantly higher prices simply based on the name.

When you compare the effects of these drugs, most users report a slightly stronger effect from Provigil®, followed by Modalert, and finally, Modvigil.

This is purely subjective, however, and could be the result of the placebo effect due to the price differences.

All three of these modafinil versions produce noticeable effects on cognition, and all three are used for the same purposes.

Is Modalert Addictive?

As we’ve discussed, modafinil binds to the same receptors as the illicit and highly addictive substance, cocaine.

Cocaine was rated the second most addictive substance in the world by Medical News Today.

This has lead many to believe that Modafinil is also highly addictive.

On top of this, modafinil is included as a schedule IV substance in the United States. This implies that despite medical benefits to the drug, it has addictive potential.

Although it’s easy to believe that modafinil is addictive based on these facts, this isn’t what the scientific literature is saying.

One study involving 105 people taking between 250 and 300 mg of modafinil per day found no evidence of tolerance formation throughout the study [4]. Researchers even concluded that the drug was a suitable candidate for psychological treatment without the risk of mood changes, tolerance, or abuse of the medication.

Another study investigated the potential for using modafinil as a treatment for cocaine addiction because it’s been shown to “blunt cocaine-induced euphoria” to reduce its potential for addiction [6].

Although modafinil is classified as an addictive compound by the US federal government, there is little evidence to suggest this is true for most people.

Can Modalert Increase IQ?

Everybody loves the idea of a drug that can make us more intelligent, as seen in movies like Limitless or Lucy. Do these drugs exist? Can modafinil give us superintelligence?

The unfortunate truth is that these drugs simply don’t exist.

Although modafinil and other nootropics can make us solve problems faster, remember things longer, and exert ourselves mentally for longer before we reach exhaustion, they don’t have any impact on our IQ.

Modalert can be used as a way to optimize the brain by allowing us to focus more intently on a specific task. We can increase productivity and our ability to focus.

When we apply this to studying, we can grow our understanding of a topic faster (though still organically) by making our study hours more efficient.

 

Conclusion

Modalert is the generic version of modafinil made by the Indian-based company Sun Pharmaceuticals.

Compared to the other main generic option available, Modvigil, it’s slightly more expensive but produces slightly stronger effects overall.

Modalert is great for those looking for a cognitive stimulant with a mild kick, but not as strong as Adderall or Ritalin. It’s great for students looking to boost their efforts while studying, for writers or artists trying to get through a creative block, or business owners managing heavy workloads that keep them working until early hours of the night.

References

1. Volkow, N. D., Fowler, J. S., Logan, J., Alexoff, D., Zhu, W., Telang, F., … & Hubbard, B. (2009). Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications. Jama, 301(11), 1148-1154.
2. Ishizuka, T., Sakamoto, Y., Sakurai, T., & Yamatodani, A. (2003). Modafinil increases histamine release in the anterior hypothalamus of rats. Neuroscience letters, 339(2), 143-146.
3. Madras, B. K., Xie, Z., Lin, Z., Jassen, A., Panas, H., Lynch, L., … & Miller, G. M. (2006). Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates the transporters and trace amine activity in vitro. Journal of Pharmacology and Experimental Therapeutics, 319(2), 561-569.
4. Nasr, S., Wendt, B., & Steiner, K. (2006). Absence of mood switch with and tolerance to modafinil: a replication study from a large private practice. Journal of affective disorders, 95(1-3), 111-114.
5. Krishnan, R., & Chary, K. V. (2015). A rare case modafinil dependence. Journal of pharmacology & pharmacotherapeutics, 6(1), 49.
6. Martínez-Raga, J., Knecht, C., & Cepeda, S. (2008). Modafinil: a useful medication for cocaine addiction? Review of the evidence from neuropharmacological, experimental and clinical studies. Current drug abuse reviews, 1(2), 213-221.

What is Modafil MD?

Modafil MD is a generic version of Provigil®. It’s made by the Indian pharmaceutical giant, INTAS Biopharmaceuticals.

INTAS makes a number of name-brand medications but has been gradually acquiring other generic medication manufacturers, like Actavis UK and Actavis Ireland from Teva Pharmaceuticals.

Modafil MD comes in two doses, 100 mg, and 200 mg. The 200 mg is the most common form carried by online suppliers.

This brand is quickly becoming a popular modafinil medication due to its unique administration method (more below).

What are the Benefits of Modafil MD?

Modafil MD is similar to other generic versions of modafinil in its effect profile, but has the benefits of faster absorption and therefore faster onset of effects.

Modafil MD is prescribed for sleep disorders like narcolepsy, extreme fatigue, shift work sleep disorder, sleep apnoea, and ADD/ADHD.

It’s used outside its prescribed uses for promoting concentration and productivity. It works primarily by increasing wakefulness and alertness for several hours.

It increases dopamine and norepinephrine concentrations in the brain, making it useful for boosting creativity and focus.

What Makes Modafil MD Different From Other Modafinil Options?

Most modafinil comes in 200 mg tablets, with some manufacturers offering 100 mg versions as well. These are meant to be taken once daily in the morning or at the start of a shift.

These pills are absorbed in the gastrointestinal tract after about 30 minutes, and begin to enter the bloodstream where they go on to exert their effects.

Modafil MD can be used in the same way, but can also be absorbed sublingually (under the tongue).

What are the Benefits of Sublingual Medications?

Underneath the tongue, you’ll find tiny blood vessels called capillaries.

These capillaries are located just under the mucous membranes of the mouth, which allow only a short distance of travel directly into the bloodstream.

By holding a medication under the tongue while it absorbs, these chemicals can travel directly into the bloodstream through the mouth.

This results in much faster absorption, and therefore quicker onset of effects.

When taking medications sublingually, the effects are felt as soon as 15 minutes afterward — rather than 45–60 minutes with the traditional oral route.

Not all medications are suitable for a sublingual application. Most other modafinil could be taken this way in theory, but have an awful taste, and special coatings to help it slide down the throat easier that block it from dissolving in the mouth as quickly as Modafil MD.

Modafil MD by INTAS is flavored with mint to eliminate the bad taste and has a thinner coating to allow the drug to begin breaking down as soon as it enters the mouth.

How Sublingual Drug Absorption Works

Taking a drug directly into the bloodstream (either sublingually, rectally, or via IV injections), follows a different path of metabolism than drugs taken via the oral route (AKA swallowing them).

When we swallow medications, they are broken down by the acidic conditions in the stomach, followed by alkaline conditions in the duodenum of the small intestine.

The medications are then exposed to bacteria and enzymes further down in the small intestines that break apart molecules as they pass through the digestive tract.

When modafinil is absorbed in this way, it goes directly to the liver for filtration. This is called “first pass metabolism.”

This first pass metabolism neutralizes some of the medication before it ever gets a chance to exert its effects.

Most of the drug, however, escapes this metabolism and goes on to exert their effects on the body.

When medications enter the bloodstream directly, however, they aren’t exposed to this first pass metabolism. They enter systemic circulation, which can then flow anywhere in the body, some to the brain, some to the limbs, others to internal organs like the liver where they’re eventually metabolized.

This often makes the effects of sublingual absorption stronger and more sudden.  

Does Sublingual Modafinil Work?

In 2009, a patent application was filed by a company called Neurohealing Pharmaceuticals.

This patent highlighted the use of modafinil sublingually, suggesting much faster absorption and a shorter duration of its effects [1].

There’s also plenty of anecdotal evidence among those using the drug to say it works.

Some Caveats with Modafil MD Sublingual Absorption

Taking medications this way allows the effects to come on much faster, but can also increase the concentrations of the drug in the bloodstream too quickly. With this comes a faster peak and higher chances of feeling side effects.

It also allows the drug to clear from the system faster.

This makes it a good mode of administration for people who want the benefits of the medication as fast as possible, as strong as possible, and for a shorter duration of time.

It’s like adding a turbo boost to your modafinil dosage.

How to Take Modafil MD Sublingually

For modafinil to absorb through the mucous membrane of the mouth and into the tiny capillaries underneath the tongue, you need to hold the entire pill under the tongue for about 15 minutes.

To make this even more effective, you can crush the pill up in your mouth to increase the surface area, and then hold this under your tongue for 5-10 minutes.

Please be aware that even with the minty flavor INTAS added to Modafil MD, it tastes god-awful (though significantly better than other forms of modafinil).

Cost of Modafil MD

Modafil MD 200 costs USD $1.48 per tablet in orders containing around 60 pills. If larger orders are made, the price reduces to about $0.89 per tablet.

This is about par with other versions of generic modafinil, such as Modalert ($0.98–$2.80), and Modvigil ($0.80-$2.10).

The most economical way to purchase Modafil MD is to buy a large quantity. Three hundred tablets will cost about $269.00. This is nearly a year supply of modafil MD for one person!

Final Thoughts On Modafil MD

Modafil MD by INTAS Biopharmaceuticals is an exciting option for modafinil users looking for the fastest onset of effects, and shorter durations.

The minty flavor, and ability to absorb the medication under the tongue makes it unique from many of the other generic versions available.

The effects of Modafil MD are comparable to Sun Pharmaceuticals Modalert and is slightly stronger than HAB Pharmaceuticals Modvigil.

References

1. Ron, E. S., Farber, N. M., Katzman, D. E., & Gamzu, E. R. (2009). U.S. Patent Application No. 11/988,695.
2. Volkow, N. D., Fowler, J. S., Logan, J., Alexoff, D., Zhu, W., Telang, F., … & Hubbard, B. (2009). Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications. Jama, 301(11), 1148-1154.
3. Wisor, J. P., Nishino, S., Sora, I., Uhl, G. H., Mignot, E., & Edgar, D. M. (2001). Dopaminergic role in stimulant-induced wakefulness. Journal of Neuroscience, 21(5), 1787-1794.

Modafinil vs. Armodafinil, What’s the Difference?

How many active ingredients are contained in modafinil? Depending on who you ask, you may get a slightly different answer.

A doctor might tell you that there is just one active constituent, modafinil! And this would be correct.

Ask a chemist, and they might tell you that there are two active ingredients, S-modafinil, and R-modafinil. They would also be correct.

How can there be two different answers to this question? How many are there?

The best way to understand this is to think about your two hands. Each one looks identical to the other, and have virtually the same functionality. Despite their similarities, they are also direct opposites of each other.

If asked to line your thumbs over top of each other, one hand is forced to flip upside down to do it. This is the same thing that happens with chemicals.

So in basic terms, there is only one modafinil chemical structure, but there are also both right and left-handed versions of it. We call these “enantiomers.”

Taking this into consideration, we can now discuss how modafinil and armodafinil are different from each other.

While modafinil has both the right-handed (R-modafinil) and left-handed (S-modafinil) versions of the drug, armodafinil only contains pure R-modafinil.

Although very similar, the effects of pure R-modafinil in products like Artvigil, are noticeably different than products containing both enantiomers (such as Modalert or Modvigil).

 

Where to Buy Artvigil

There are many online vendors selling Artvigil. Unfortunately, many of them are low quality, and some are even complete scams. Online modafinil and armodafinil vendors are notorious for poor customer service, long delivery times, and questionable business practices.

For this reason, we always try to recommend sources that we use and have found to be reliable, and affordable. Our current favourite source for Artvigil is AfinilExpress.com.

If you use the coupon code MODAFINILOTC during checkout, you can save 10% on your order. 

Patent Wars: Nuvigil® vs. Artvigil

Nuvigil® is the brand name version of pure R-modafinil produced by Cephalon Inc. They were the original manufacturers of the drug after they purchased the French research company that invented it, Lafon Labs.

Cephalon Inc paid 450 million dollars to acquire Lafon Labs specifically so that they could secure the exclusive rights to sell their flagship product, Provigil® (modafinil).

Along with modafinil, Cephalon Inc was able to produce the pure (enantiopure) R-modafinil, which they call Nuvigil®.

Cephalon Inc was the exclusive manufacturer of the drug for several years, collecting massive profits thanks to patent laws.

Several generic manufacturing companies, such as Actavis, and Sun Pharmaceuticals began challenging these patents in 2014, which they won, allowing other manufacturers to produce their own version of the drug.

This was a significant loss for Cephalon Inc, who still holds the patents for armodafinil until 2023.

Other Generic Versions of Armodafinil

1. Acronite (by Consern Pharma) — India
2. Armoda — ACI Pharmaceuticals (Symbiota), Bangladesh
3. Armod — India (discontinued)
4. Neoresotyl — Chile
5. R-Modawake — India
6. Waklert — (by Sun Pharma) India

What’s the Dose for Artvigil?

Artvigil is recommended by the manufacturer to be taken in doses of 150 mg per day (1 tablet). This is the standard dosage for armodafinil across the board, including both Nuvigil® and Waklert.

Exceeding 150 mg of armodafinil increases the chances of developing side effects.

Armodafinil has a longer half-life than modafinil, which means that it lasts longer in the body. Therefore, it’s recommended that only one dose of armodafinil is taken per day to avoid overstimulation in the evening when it’s time to go to sleep.

Some people are more sensitive to the effects of armodafinil and require a smaller dose. Artvigil makes this process simple by making their tablets with a crease down the center.

This makes it easy to split the pill into two identical 75 mg doses.

Managing Side-Effects of Armodafinil

Some people report no side effects after a single use but experience a gradual onset of side effects after a week or more of repeated armodafinil usage.

This is due to the half-life of the medication.

A half-life is a common way of measuring the duration of effects a drug has in the body. It’s a measurement of how much time it takes for exactly half of the medication to be cleared from the body.

If a new dose is taken before the drug has completely cleared, the concentration will increase above the recommended level.

This measurement is then used to calculate how often a dose of a medication should be taken.

The half-life of Artvigil is reported to be around 13 hours [1]. This means that if a new dose is taken at the 13-hour mark, we will have approximately 1.5 times the normal dose in the body (the full new dose plus the 50% remaining on the last dose).

To avoid compounding the concentrations of the drug in the bloodstream, it’s important to avoid taking more than one per day and have breaks where no medication is taken to help the body eliminate buildups of the drug.

It’s usually recommended to take at least one day off per week and one week off per month of Artvigil.

Summary of Artvigil: Should I Buy Some?

Artvigil is the cheapest form of armodafinil but has slightly less potency when compared to Nuvigil® or Waklert.

It’s considered one of the best pharmaceutical nootropics for improving focus, concentration, mem

ory, and wakefulness. This makes it useful for anybody who needs to remain awake and vigilant.

This often includes students cramming for an exam, office workers trying to finish a tough project, writers and artists, as well as military special forces on long overnight missions.

We highly recommend Artivigil if you’re looking for a strong boost in productivity and don’t mind the possibility of having some minor side effects like insomnia.

References

1. Darwish, M., Kirby, M., Hellriegel, E. T., & Robertson, P. (2009). Armodafinil and modafinil have substantially different pharmacokinetic profiles despite having the same terminal half-lives. Clinical drug investigation, 29(9), 613-623.