Tretinoin is a medication primarily used topically to treat acne and reduce signs of aging, working by promoting skin cell turnover. Nootropics, on the other hand, are substances (including drugs, supplements, or other substances) that may enhance cognitive function, particularly executive functions, memory, creativity, or motivation.
There’s no specific information or documented interactions between the use of nootropics and tretinoin. They work on different systems (the skin for tretinoin and the central nervous system for many nootropics) and are generally used for different purposes.
However, both nootropics and tretinoin can have side effects.
Your skin may become inflamed when using tretinoin for the first time. During the first few weeks of treatment, mild to severe erythema (redness), dryness, peeling, and itching are frequent; over 60% of patients report experiencing these side effects. But taking specific safety measures can lessen the negative effects. These negative effects ought to gradually disappear as the skin adjusts to the medication.
However, tretinoin should be stopped and a doctor should be seen if discomfort persists after a few weeks, or if you experience any of the following symptoms:
- Discomfort that lasts forever or gets worse
- Blistering, crusting, edema and a great deal of redness
- A quick, brief alteration in the colour of the skin
If you’re considering using nootropics while also using tretinoin, it would be best to consult with a healthcare provider.